I will do my best to keep this explanation simple - but no promises. :lol: Approx. 80% of a person's immune system is in their gut. That means the stomach, large and small intestine. We have both good and bad bacteria. *Most* people (by natural health standards) have an overrun of bad bacteria compared to their good bacteria. A good probiotic can bring the gut bacteria back into balance so the good once again outweighs the bad.
ITP is an issue of the immune system (really, all disease is, but that's for another post). That being the case, one needs to look at the gut. It makes sense that a person *could* respond positively with their platelets if one of things causing their ITP happens to be an overrun of that gut bacteria. H Pylori is one that sometimes can get a hold for ITP patients. But I'm even thinking of the other more common bacterias. Klebsella pneumonaie, streptococcus, etc. There are a multitude of them.
Because you seem to respond to the probiotics positively in terms of your platelet count it might be really worth your while to get a stool test done from Genova Diagnostics. It can tell you EVERY bacteria in your gut, if you have enough good vs. bad, and what substances (both antibiotics - which I don't recommend- and natural substances) will kill off the overrun of bad bacteria. This may prove very beneficial to your health long term since you are responding to the probiotics so easily. Typically, one finds that oil of oregano, uva ursi, and plant tannins are common substances that will kill off the overrun of bacteria. A stool test will test the bad bacteria to multiple substances to see what it is sensitive to. In your case, this would seem really worth your while.
It's actually quite a good thing that your body responds this way. Not many respond to probiotics so quickly in terms of gut repair (immune repair).
hope this helps,
patti