Diet and platelet count

On New Years I decided to go on a diet. Not to lose weight, I just wanted to feel better and have more energy so I cut out all processed foods and have been eating clean and exercising for the last two weeks. I was feeling pretty amazing until the brain fog and bruising came! This is the second time I have caused a platelet crash by doing this! Side note.. I’ve been on promacta for years and my count is usually somewhere around 60,000- 80,000. Anyway, I just realized that the healthier I am the lower my platelet count is. I wonder if it is because my immune system is stronger and killing more platelets?
Has anyone else experienced something similar?

Hii! My two major crashes (after year long remissions) were after dieting. I was overweight most of my life. In 2013 i lost 20lbs and around that time.. boom! platelets under 10... then in August 2017, after regaining all the weight and being in remission for 4.5yrs, I started excercising and dieting again (slowly, didn't want the yoyo effect). In November that year my platelets crashed again. I have been watching what I eat since then and my ITP has become chronic... I have no idea if it is all connected but it does seem to be to some extent

Wow, that sounds frustrating. The joys of ITP...
Hematologist have any ideas? Any other diagnosis that could be the culprit?

I have an appointment on Thursday and I’m excited to hear her thoughts on this!

Meliss wrote:
... I just wanted to feel better and have more energy so I cut out all processed foods and have been eating clean and exercising for the last two weeks...

Exercise? Take a look at this thread. Excercise / Flu / Folate trifecta at work?
pdsa.org/discussion-group/7-treatment-general/30169-no-response-to-ivig-ack.html#64535

Meliss wrote: ...I’ve been on promacta for years and my count is usually somewhere around 60,000- 80,000. Anyway, I just realized that the healthier I am the lower my platelet count is. I wonder if it is because my immune system is stronger and killing more platelets?
Has anyone else experienced something similar?

I can't say that I have. I've been on Promacta for over a year now, still actually trying to get to the lowest dose possible (bit of a roller coaster), but my diet has been mostly Paleo (started with 6 months of AIP) for nearly two years now. Been going to Crossfit since last March.
Ultimately, I have experienced the things you're looking for... more energy, less brain fog, less bloating, etc, without any crashes in platelets.
Based on AIP and Paleo belief systems, you could have trigger foods that are causing inflammation, and thus an immune response.
Also, It's my understanding that harder exercise isn't the best idea for people with autoimmune issues for similar reasons. You're tearing your body down to build it back stronger... I still do CrossFit anyway.
In my relatively short experience with ITP (not even 2 years yet), so much of what I've seen and read is that each of us individually has to figure out what works best for us. That includes all aspects of diet and lifestyle. What we all tend to think is good for us, isn't necessarily good for an individual.
I hope you figure out what's causing your crash!

when you go on a diet you could be depriving your body of certain vitamins, minerals, protein you need. just because you feel better after going on a diet doesn't mean that you now aren't lacking in something that causes your ITP to flare up.

if you exercise you need more protein more nutrients to recover... if you don't increase your protein and add other nutrients you can deplete things that made you stay in remission... hence ITP comes back.

Every time I try to lose a little weight either through a "healthier food" diet or increased exercise I seem to crash. Then it takes weeks to make up for that crash. Good luck. Please keep us posted!