Nplate and Gout

I'm curious about if anyone has experienced frequent gout flareups while on Nplate. I started Nplate injections in mid December and I've had 4 flareups so far in past 2 months and this last flareup was in my hand. I've had infrequent gout attacks over the past 12 years but very rare in past 2 years. Flareups started when prednisone taper went to 5mg daily and then when prednisone was stopped altogether the flareups were severe and this last episode was in my hand . I have never had an attack in my hand before just in my foot. Each of the past 4 flareups were treated with a 6 day methylprednisolone treatment which is setting me back with ending this horrible prednisone withdrawal.

I would think that the gout flares would be more related to tapering Prednisone than starting N-Plate. Since Prednisone is an immunosuppressant, it masks inflammation and autoimmune problems which can come back full force once the drug is stopped.

I agree with Sandi. As I had a gout flair last summer prior to ITP regression and had four day of prednisone.

Are you taking Allopurinol? My Nephrologist put me on that as a daily. I hear you on the tapering trouble. It is no fun and hard to get set back.