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ITP, allergies, asthma and IgA deficiency?!?

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12 years 9 months ago #34848 by Melanie37
Hey everyone!

I've been diagnosed with ITP for about 3 years. Luckily, my platelets usually range anywhere from 60-100 (not too bad at all, but enough to be annoying). I also have really bad allergies and asthma. Recently saw an allergist/immunologist and he thinks my IgA or IgG levels might be low which could be the cause of my ITP (also have a family history of hypothyroidism and celiac disease), and that perhaps I have a "bad immune system." Not confirmed yet, just got the blood drawn today.

Does anyone else have this deficiency? IgG or IgA?

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12 years 9 months ago #34852 by Ann
There's a few of us talking about this on a thread entitled 'CVID'. You might want to join in. Symptoms of low IGs is infections, do you get chest, sinus and/or ear infections regularly?

You should be tested for IgM, IgA, IgG and the subsets of IgG... 1, 2, 3 and 4. I am low in IgG2 and 3 and IgA. My total IgG is around 4.5 (or 450 depending on how it's written) and the immunologist won't treat unless and until it gets down to 3. There is no treatment available for low IgA.

Let us know your results.

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12 years 9 months ago #34862 by MommaBee
Replied by MommaBee on topic ITP, allergies, asthma and IgA deficiency?!?
Not very educated altogether about this area but I do know if you have this deficiency as mentioned usually frequent infections... But also it can "mask" celiac blood tests making them negative as they don't rise enough so given your family history if you do have this deficiency you may want or need further testing for celiac? You may need genetic blood.tests for it (hla DQ 2 or 8 gene) or.potentially a GI scope to be sure if you do/don't have it... Hopefully it all just.comes back in the normal range!

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