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New approach to autoimmune diseases.

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13 years 5 months ago #29449 by lili
Replied by lili on topic New approach to autoimmune diseases.
This is very exciting. This would be a cure, if they can get it working in humans.

Thanks for posting this,

Lily

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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13 years 5 months ago #29450 by Sandi
Replied by Sandi on topic New approach to autoimmune diseases.
It sounds a bit like science fiction, but I guess that is the century we are living in. So if you have no spleen then, it won't work?

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  • weirdjack
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13 years 5 months ago #29467 by weirdjack
Replied by weirdjack on topic New approach to autoimmune diseases.
However, it was hideously expensive. “It cost probably about a million dollars to treat 10 patients using live cells,” he said.

"hideously expensive"? Relatively speaking, the stuff isn't all THAT expensive.
Consider that Promacta treatment is around $5k-$6k per month for a 50mg dosage. His 'million dollars' would only cover 18 months of Promacta to treat those same 10 people! And that is just for maintenance.
$100,000 cost to treat 1 person is peanuts if it works as hoped for. Heck, at $6k per month, I've used over $200,000 worth of Promacta in just the past 3 years.
We could use some new approaches!

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13 years 5 months ago #29471 by Mark
Replied by Mark on topic New approach to autoimmune diseases.
This could be a big breakthrough and is outside the box thinking.

Cost is likely to come down -

Sandi- the thymus and lymphoid system also function in inducing self-tolerance.

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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13 years 5 months ago #29473 by Sandi
Replied by Sandi on topic New approach to autoimmune diseases.
This worked just as well in mice. It only takes an hour in a chemical bath to attach little bits of myelin to the nanoparticles of PLG. When infused into a vein, they’re carried by the blood right to the spleen, where the nanoparticles “meet” the T-cells.

Yes, but this seems to be specific, or maybe the article just didn't give enough detail. I don't know.

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