Question

I had a stroke on nplate a year ago I believe the doctor was at fault they kept making my platelets go over 200 and if they weren't at 200 they would increase I'm thinking of trying nplate again because right now I am using ivig and it's slowly not working as well as it was and I don't want to lose my emergency medicine incase of a car accident or something like that and even when I decide to have kids I know ivig is a safe treatment during pregnancy I just wanted some feedback from you guys thanks hope everyone's well

Why would you want to try Nplate again if it is what caused a stroke? Why do you feel the Dr is at fault?
200k is great, but I do not see why they would increase the Nplate at 200k(if that is what you are refering to)

If the doctor was aiming for a count of 200 then they are most definitely at fault as they are supposed to aim for a count of around 50 in order to avoid clotting events. What I would do is find another doctor, ensuring that they are experienced with treating ITP, and ask their opinion.

Ann wrote: If the doctor was aiming for a count of 200 then they are most definitely at fault as they are supposed to aim for a count of around 50 in order to avoid clotting events. What I would do is find another doctor, ensuring that they are experienced with treating ITP, and ask their opinion.

So, with Nplate you do not want counts at 200k?

Dean wrote: So, with Nplate you do not want counts at 200k?

No, because all the platelets you have are new and large and extra beefy, too many can cause clotting.

The UK guidelines from the manufacturer say at a count of 150 you reduce the dose and a count of 250 you withhold the drug until the count falls.

I also asked to be tested for APS because that also tends towards clotting and would suggest that everyone on Nplate does the same.

Thanks Ann. I was not aware of that with Nplate.

I would be happy at 50 I don't need a hundred or a remission would be nice lol but yes don't ever let them get over 180 on nplate I'm proof you could have a stroke and I don't want anyone to have to go through that it was horrible

And yes 200 is great for people who have normal platelets

Thanks for the education! My NPlate treatment has got me up to 50 on a relatively low dose. I should make sure it doesn't rise condsiderably higher than this! I do feel quite fortunate to respond to this treatment though - side effects are negligible, so far so good.