Aquired platelet dysfunction question

Hi all,
Will try to keep this short, here goes.
My 5 yr old has had ITP for 2 yrs.
Approx. 16 IVIG treatments
4months on 6mp
BMB clean
Platelets are no longer bottoming out but there are more strange things going on. He used to only bruise and have petechia with counts under 30. Now he is getting them in the 80's. PFA test came back with abnormal bleeding time but as we know these test are not accurate. Test sent off to Wisconsin and they washed his platelets to see if there was an antibody left attached. There was nothing. Normally with ITP she said there would at least be some antibody found. BUT, she also said that this test is not accurate or it would be a test to diagnose ITP. The lab could not diagnose ITP or rule it out. So now they are going to attempt a platelet aggregation test even though platelets are not normal. No one in the family has a bleeding disorder. My question is, has anyone had a problem with an aquired platelet dysfunction as a result of ITP treatments like 6mp or IVIG. Or just had ITP as secondary diagnoses to an aquired dysfunction?? Thanks for any ideas, this is such a miserable frustrating mess, especially for my son.

Well I am new here and not able to answer your question, but I'm sure someone will be able to give you some answers. I just wanted to say hello and sorry to hear what your son is going through.

I would doubt that ITP treatments would cause an acquired platelet dysfunction, however, many people with ITP also have platelet function problems. Where is he getting the petechiae? How bad are they? Does he have any bruising or bleeding at 80k?

A few people here have tested negative for ITP antibodies. You're right, it doesn't mean much. It could be that the antibody your son has just isn't discovered yet or he has antibodies that affect platelet production. They don't test for those (too new, no tests available outside of research labs).

Thanks Banana!

Sandi,
His petechia is in random places, not in any certain spot.
I attached a pic of just his legs when his platelet count was 89K.
He never looked like this before unless he was below 30.
Very strange.

Is that petechiae? Looks like bruising in the pic. Wow - nasty for 89k.

That is mostly bruising, the petechia is mixed in, scattered.