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CTLA4 Gene - Autoimmunity

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9 years 4 months ago #57204 by DelnStyle
CTLA4 Gene - Autoimmunity was created by DelnStyle
Hello Everyone:

There's been a massive breakthrough which may explain (for some of you) why you may have ITP episodes. There has been a proven and definitive link to the CTLA-4 gene. See below for further reading on it.

en.wikipedia.org/wiki/CTLA-4

www.cincinnatichildrens.org/service/d/diagnostic-labs/molecular-genetics/custom-gene-sequencing/ctla4

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  • Hal9000
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  • Give me all your platelets and nobody gets hurt
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9 years 3 months ago #57879 by Hal9000
Replied by Hal9000 on topic CTLA4 Gene - Autoimmunity
I see that the Wikipedia article talks about the drug 'Abatacept' which has been developed to counter the effects of the CTLA4 gene on the immune system.
en.wikipedia.org/wiki/Abatacept

But it appears that the drug has only proven effective for Rheumatoid Arthritis (RA). Anyone hear of a theory as to why it doesn't work for ITP or any other auto immune diseases?
ITP Types and Treatments by HAL

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Platelet Disorder Support Association

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IMPORTANT!

The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.