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What is the difference between IVIg and WinRho

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15 years 1 month ago #7103 by kmcadams
Call me goofy, but can someone pls explain the difference. My son has had IVIg but seems kinda pointless considering the shortness of time it works for him..8 days once, and about 2 wks the second time till back in the 20's. Does WinRho last longer? Why do they try IVIg first?
  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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15 years 1 month ago #7106 by Sandi
I think they use IVIG first because it's been around longer and it used to be first-line protocol. I had Win-Rho first, never had IVIG.

Win-Rho can work longer in those who respond. Some get a month, some get several months. I didn't get any response, so it wasn't an option for me. If it were, I would have used it because of the quick infusion time. I had the 5 minute push so it was very fast.
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15 years 1 month ago #7127 by athos45
whats the difference in price tag? Here in the Phils we have to pay for everything....
The medical card even has a clause that ITP isnt included in coverage.... :(

Father of Tonio, 8 yrs old w Chronic ITP
15 years 1 month ago #7135 by
kmcadams I wasn't given IVIg first - when I refused prednisone again my hematologist checked with my insurance and I had WinRho. My hematologist told me she never had anyone go into remission with IVIg.

The differences can be found in the treatment section:

www.pdsa.org/treatments/conventional/anti-d.html?layout=item
Anti-D [WinRho]
Anti-D (also known as Rho(D) immune globulin intravenous or anti-D IGIV) is a blood product consisting of antibodies to the RH factor on red blood cells. It achieves a temporary rise in the platelet count in about 80 percent of people and occasionally has a longer term effect

www.pdsa.org/treatments/conventional/immunoglobulins.html?layout=item
IVIg (Intravenous Infusion of Immunoglobulins)
IVIg is a solution of IgG antibodies normally present in adult human blood.1 The IgG antibodies are extracted from the combined plasma of more than 1,000 screened donors and treated to eliminate bacterial and viral contaminants. .....
IVIg temporarily increases the platelet count in about 80% of ITP patients.2 The duration of the response varies and the treatment can be repeated when the platelet count drops.