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Switching from Nplate to Rituxan?

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10 years 1 month ago #51068 by daughter2
Switching from Nplate to Rituxan? was created by daughter2
Hi, my 72 years mother has been getting weekly (sometimes every two weeks) Nplate injections for the last 6-7 years. My mother is also on a low dose daily prednisone pill (about 6-7mg). Her number had been very stable until 6 months ago. Her number now is very unpredictable and she has had a few emergency platelet transfusions done at the hospital as a result.

Her doctor is recommending switching her from Nplate to Rituxan.

Has anyone here known of a case like this? Switching from long term Nplate use to Rituxan? Her doctor had admitted that she has never done this type of switch before so my mother will be her first patient case... it makes us kids very uneasy for my mother to be the guinea pig without a plan in place.

Any advice or recommendations will be greatly appreciated!
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10 years 1 month ago #51070 by Ann
Replied by Ann on topic Switching from Nplate to Rituxan?
People have done all sorts of different treatments in all sorts of order. Rituxan has something like a 50% to 60% chance of success and it makes no difference that she's come from Nplate. It will either work or not. Shame about the Nplate not working properly. It worked for me and after three years pushed me into a sort of remission.
  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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10 years 1 month ago #51074 by Sandi
Replied by Sandi on topic Switching from Nplate to Rituxan?
Rituxan can take 40 to 12 weeks to work, so it would be wise to continue some sort of treatment while waiting. Also, not everyone responds to Rituxan so you have to be prepared for that.