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Antibiotics effecting Promacta

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11 years 4 months ago #43907 by GhostRider
Antibiotics effecting Promacta was created by GhostRider
So during the last few months I have been taking 25mg of Promacta daily and my counts have been hovering around the 100 mark. Everything was good.

Now, my immunologist insisted that I start taking zithromax (azithromycin) as I have CVID. She neglected to tell me or my Hemo that one of the common side effects was oral thrush.

Apparently this is quite normal however of course it needed to be treated and with me having CVID it was treated with penicillin.

Now the zithromax combined with the penicillin hit count. From me doing nicely it dropped to 22. My Hemo immediately took me of the zithromax which was good as I hated the stuff, apart from oral thrush it also gave me a really bad stomach.

A week later my count has crept up to 33..

Just wondering if anybody has had this and how long for your count to go back up if it did.

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11 years 4 months ago #43912 by Rob16
Replied by Rob16 on topic Antibiotics effecting Promacta
Did you intend to say that your doctor treated oral thrush with penicillin? Both Zmax and penicillin are antibiotics and both cause oral thrush. Nystatin and fluconazole are the usual treatments.

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11 years 4 months ago #43922 by Ann
Replied by Ann on topic Antibiotics effecting Promacta
I tried the azithromycin and couldn't tolerate it either. So I take Septrin every day. It works wonders at keeping some infections at bay and no side effects.

Any and all antibiotics can cause thrush. I've been lucky so far but know that it's something to look out for.

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11 years 4 months ago #43924 by GhostRider
Replied by GhostRider on topic Antibiotics effecting Promacta
phenoxymethylpenicillin or Penicillin V can be used for treating oral thrush. Since I was diagnosed with cvid my gp will err on the side of caution.

Ann I will have mention that to my immunologist but I am not holding my breath

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11 years 4 months ago #43925 by Ann
Replied by Ann on topic Antibiotics effecting Promacta
I should think that the immunologist will want you to take some antibiotic. If you say that you can't tolerate the azith, he'll have to offer you something else. If you have to take a drug for ever as we do then it has to be something that you can live with.

It's good that you have a GP who supports you. Mine does too. It makes a difference.

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11 years 4 months ago - 11 years 4 months ago #43929 by Sandi
Replied by Sandi on topic Antibiotics effecting Promacta
I've never heard of using Penicillin for thrush either. I thought it caused it. I've always used either Mycelex or Nystatin. Are you sure about that? I couldn't find any info about using Penicillin for thrush.

Anyway, to answer your question, yes, counts can rebound.

And I agree with Ann about the antibiotic. It's up to the doctor to find a way to treat the CVID so that you are able to live without side effects. I've been on antibiotics that caused stomach upset like that and I ended up with massive uncontrollable diarrhea. You can't go out of the house. Just insist that he prescribe something else.

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