Nplate remission

Has anyone had remission after coming of Nplate thanks marosa

I've only had 5 injections so far and getting 6th one on Thursday. Last count was 22k.

Hi amberyard I've just came of Nplate 5weeks ago after taking it for 1 year count was 380 when I came of it then 225 next week then 67 week later 19 then last week went up to 45 on its own unbelievable i was taken of Nplate because of pain in my feet consultant thinks I had rare side effect of peripheral neuropathy so waiting to see neurologist I was due to start immunoglobins and mycophenalate but consultant has decided not to treat while count of 45 if it stays up maybe Nplate has done some good hoping you fare well with it take care marosa

Hi Marosa,

I have gone from 1µg/kg to 3µg/kg in just under a year. An incompetent hematologist covering the regular doc one week skipped the 2µg/kg injection one week with the result that platelets fell from 181/nL to 13/nl the next week. This occurred five months into Nplate therapy. He evidently disregarded Amgen's dosing instructions in the insert.

My hematologist wants to terminate Nplate injections of 3µg/kg weekly after one year of therapy, so I have the same question as you. Googling "Nplate cessation remission" failed to find anything worthwhile. Amgen's patient support remains noncommittal with the basic recommendation that it is the physician's prerogative. Amgen's rep did repeat the insert warning about falling platelets upon terminating treatment, but that was it.

Based on the hematologists' performance so far, that idea is not reassuring. I would be very interested in your results.