Promacta and Nausea

I'm considering starting Promacta since pred doesn't seem to work quite as well as it used to for me. I've noted that some of you Promacta-users have complained of nausea. If this is your case, have other meds given you nausea as well? (I'm trying to predict if I will have nausea. All opiates and general anesthetics make me REALLY nauseated. I'm wondering if that's an indication that Promacta too will give me nausea.)

If Promacta does give you nausea, what have you done to deal with it? Did it get better on its own?

I have nausea all day long when I'm taking Promacta. I spoke to my pharmacist, she says out of all patients that are taking Promacta, I'm the only one that complained of nausea. There are about 10% of people that get nausea. My dr then gave me Granisetron to take 1 hr before taking Promacta. However, I haven't taken it yet...I wanted to see if my nausea gets better...which it is. But, I also have fatigue too...other then that, I'm getting good results from Promacta.

Had a lot of nausea at first with Promacta. I adjusted to it and things got better over time. Promacta has been the least invasive and best working treatment that I have used over the past ten years. It worked very well with minimal hassle for 3 years.
But remember, everyone is different.
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Weirdjack,

Can you please tell me when your nausea went away? I've been on Promacta for 3 weeks now...the nausea is better, but still there. And my appetite is gone...guess that goes along with feeling nauseous...

Can you please tell me when your nausea went away? I've been on Promacta for 3 weeks now.

Give it a bit more than 3 weeks....it gets better. Oddly enough, I found that a small bit of cheese an hour or so after taking Promacta helped with nausea. Not an entire wheel, but just a couple of bites settled my stomach. If you are in a state where medical cannabis is legal, that can help with nausea.
The 'appetite loss' stayed with me to some degree. I lost over 30 pounds in the first 2 years on Promacta, without really changing anything I did. Part of it was due to the mild appetite loss, part (I believe) was due to increased platelet production. Creating those extra platelets burns more of what you take in.
Of course, in the months I've been off Promacta and back on Dex and then Cellcept, I've gained it all back again. That's life!

Above all...remember that everyone is different. What worked for me may not work for everyone.
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Thanks weirdjack.

I wished medical cannabis was legal here in Texas...

Being nauseous is not a good feeling at all, especially since it's throughout the day. However, I will take it if the platelet counts and liver functions are ok.

I understand nausea all day long not being fun. Hang in there.
I know it seems odd, but a small bit of cheese really did help me. Extra sharp cheddar or such worked for me. I just ate a small bit. Even just one stick of string cheese worked also. I know there are some dairy warnings for Promacta. A piece of cheese didn't affect me adversely and it stopped the nausea immediately. Yep...seems odd, doesn't it?
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Yes, that does sound odd. I'm not a big cheese eater. But, I'm willing to try. When do you eat the cheese? 4 hours before or after taking Promacta?

I went to Cleveland clinic yesterday. I am in Nplate now but doc may eventually want to switch me to Promacta but don't know if I want to feel nauseous all of the time. I don't have symptoms on Nplate but am getting kind of annoyed with weekly CBC's.

When do you eat the cheese? 4 hours before or after taking Promacta?

There is no formula for this. I always took Promacta in the early morning...around 1:00-2:00am usually, then went back to sleep. If I felt a little nausea when I got up at 5:00am, I ate a little cheese. For me, that settled my stomach.
But hey, everyone is different. What works for me may not work for others.
What do you normally do when you feel nauseated?
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I try to eat some crackers to see if that helps. Now days, nothing taste good anymore. I don't even want to eat. I just want a fruit smoothie and I'm satisfied with that. The thought of food makes me feel worse.