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Promacta anyone taken?

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12 years 5 months ago #35744 by luca
Replied by luca on topic Promacta anyone taken?
Thanks for your reply! When you say the Promacta "didn't work," was that because your numbers were so inconsistent, or did you actually "crash" despite the 75 mg dose you had been taking? I guess what I'm wondering is how your doc defined "failure" on Promacta. I hope the Nplate gives you better stability, but I'm not sure what the difference between the two drugs is (they are both TPO's, yet some people do better on one over the other). Does anyone else have any info on these differences??!!

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12 years 5 months ago - 12 years 5 months ago #35755 by Ann
Replied by Ann on topic Promacta anyone taken?

luca wrote: Does anyone else have any info on these differences??!!


Nplate is a peptide mimetic that binds to the distal hematopoietic receptor domain.

Promacta is a non-peptide mimetic that binds to the transmembrane domain.

So there you are!
The following user(s) said Thank You: amberyard

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  • amberyard
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  • Lowest count 0-1k highest count 1,247,000 11/2/21. 189,000 N-Plate 527 Weekly CBC
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12 years 5 months ago #35763 by amberyard
Replied by amberyard on topic Promacta anyone taken?
Numbers didn't get to 50k in the 2 months I was on it.

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12 years 5 months ago #35766 by jeffrey71
Replied by jeffrey71 on topic Promacta anyone taken?
Thinking of you Amber! You keep fighting and do not surrender!

Jeffrey

PS Vent at will! :angry:
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Platelet Disorder Support Association

Platelet Disorder Support Association
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IMPORTANT!

The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.