Remember Me     Forgot Login?   Sign up   •  Web site Help & Info

!!! DISCUSSION GROUP RULES !!!

1. You must be a registered website user in order to post and comment. Guests may read only.
2. Be kind and helpful, not rude and cynical.
3. Don't advertise or promote anything. You will be banned from the group.
4. Report problems to the moderators. THANK YOU!

Article re: pros and cons of treatments

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
11 years 9 months ago #32487 by Sandi
I came across this article today and have no idea how I missed it in my Bloodjournal updates. It's one of the most thorough treatment articles I've ever read, listing pros and cons of three common treatments.

bloodjournal.hematologylibrary.org/content/120/5/960.full?sid=9e00c230-10f8-405a-964d-299484e271a0
The following user(s) said Thank You: Nomad, Dori, Fervenz, johnmerrick

Please Log in or Create an account to join the conversation.

  • CindyAnn
  • Offline
  • Diagnosed Jan 10, 2008. Rituxan treatment in May 2009. Treated with Prednisone off and on until 08/23/17 - 12.5mg Promacta as of 10/22/17
More
11 years 9 months ago #32493 by CindyAnn
Replied by CindyAnn on topic Article re: pros and cons of treatments
This article sure makes a good argument for delaying a splenectomy. It also points out the many choices we as "ITPers" have to make.

Very good read!!!

Cindy Ann

Please Log in or Create an account to join the conversation.

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
11 years 9 months ago #32505 by Sandi
Replied by Sandi on topic Article re: pros and cons of treatments
I think the article presents both sides well, but does give examples of when it is best to consider it and best not to.

Please Log in or Create an account to join the conversation.

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
11 years 9 months ago #32514 by Sandi

Please Log in or Create an account to join the conversation.

More
11 years 9 months ago #32523 by Vdeutsch85
Replied by Vdeutsch85 on topic Article re: pros and cons of treatments
Great article, one article says to wait 1-2 years before considering splenectomy and the other says 3

Please Log in or Create an account to join the conversation.

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
11 years 9 months ago #32528 by Sandi
Replied by Sandi on topic Article re: pros and cons of treatments
I looked to see the time difference between the two articles...only 8 months. Different authors too. Oh well, safe to say they advise to wait one to three years!

Please Log in or Create an account to join the conversation.

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
11 years 9 months ago #32548 by Sandi

Please Log in or Create an account to join the conversation.

More
11 years 9 months ago #32554 by Vdeutsch85
Replied by Vdeutsch85 on topic Article re: pros and cons of treatments
I think I will re-assess my situation in December....that will be the one year point for me. However, the more I read, the more against splenectomies I become.

Please Log in or Create an account to join the conversation.

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
11 years 8 months ago #33247 by Sandi
Replied by Sandi on topic Article re: pros and cons of treatments
Here is a new article re: Rituxan and Dexamethasone. This has been published before, but the more this combination is studied, the more credible it becomes.

onlinelibrary.wiley.com/doi/10.1111/ejh.12102/abstract
The following user(s) said Thank You: Dori

Please Log in or Create an account to join the conversation.

More
11 years 8 months ago #33255 by Vdeutsch85
Replied by Vdeutsch85 on topic Article re: pros and cons of treatments
Thank you for sharing!

Please Log in or Create an account to join the conversation.

More
9 years 10 months ago #47722 by goaliegirl51
Replied by goaliegirl51 on topic Article re: pros and cons of treatments
I had a laproscopic splenectomy after having all possible treatments attempted. It worked great for about a month. Then my platelets plummeted again. I now have an n-plate injection every week.

Please Log in or Create an account to join the conversation.

  • EmilyK
  • Offline
  • Diagnosed jan 2015 at age 50 with 13,000 platelets.
More
9 years 10 months ago #47723 by EmilyK
Replied by EmilyK on topic Article re: pros and cons of treatments
How is the NPlate working for you?

Please Log in or Create an account to join the conversation.

More
9 years 10 months ago #47725 by goaliegirl51
Replied by goaliegirl51 on topic Article re: pros and cons of treatments
Well it does the job. Generally you're supposed to keep the platelets between 50,000 and 150,000, but I'm so messed up I don't actually follow all of the FDA recommendations. In general though, I'd say it's painless. You have to stay on top of it. If you miss a dose, your count will plummet. My doctor advised me to use Nplate instead of the promacta pill because apparently the pill is a bigger pain and diet restrictions. Supposedly most people dislike the pill way more than Nplate.

Please Log in or Create an account to join the conversation.

  • Sandi
  • Topic Author
  • Offline
  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
9 years 9 months ago #48147 by Sandi
Replied by Sandi on topic Article re: pros and cons of treatments
Goalie:

It's in your best interest to follow the Guidelines for N-Plate. Not doing so can be dangerous. Counts should actually be maintained around 50k and your doctor should be dosing you in that manner.

Please Log in or Create an account to join the conversation.

  • mrsb04
  • Offline
  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
More
9 years 9 months ago #48150 by mrsb04
Replied by mrsb04 on topic Article re: pros and cons of treatments
Interesting reads thank you Sandi

Please Log in or Create an account to join the conversation.