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Rituxan and serum sickness

  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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14 years 4 months ago #18466 by Sandi
Rituxan and serum sickness was created by Sandi
This article is a little bit old (2007), but it's the first one I've seen that addresses serum sickness in those with ITP and rheumatological disorders:

www.mskreport.com/articles.cfm?articleID=1172

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14 years 4 months ago #18560 by barrelgal
Replied by barrelgal on topic Re: Rituxan and serum sickness
Interesting article. I wish there was a study out there reguarding what effect pre-treatment drugs (Benedryl, Tylenol, steroids) have on serum sickness or even reactions during recieving rituxan. My hema insisted that I pre-treat with all 3 before rituxan, but I did talk him down to only getting 5mg of dex pre-treat by then end of my runs with rituxan.
So many variables with all this, I know there isn't the possibility to do a study with them all, but one could hope...

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
More
14 years 4 months ago #18568 by Sandi
Replied by Sandi on topic Re: Rituxan and serum sickness
Usually the pre-meds will prevent during-infusion reactions, but not the delayed ones. They used to be protocol, not sure if they still are.

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The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.