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Rituxan and serum sickness

  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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14 years 2 weeks ago #18466 by Sandi
Rituxan and serum sickness was created by Sandi
This article is a little bit old (2007), but it's the first one I've seen that addresses serum sickness in those with ITP and rheumatological disorders:

www.mskreport.com/articles.cfm?articleID=1172
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14 years 2 weeks ago #18560 by barrelgal
Replied by barrelgal on topic Re: Rituxan and serum sickness
Interesting article. I wish there was a study out there reguarding what effect pre-treatment drugs (Benedryl, Tylenol, steroids) have on serum sickness or even reactions during recieving rituxan. My hema insisted that I pre-treat with all 3 before rituxan, but I did talk him down to only getting 5mg of dex pre-treat by then end of my runs with rituxan.
So many variables with all this, I know there isn't the possibility to do a study with them all, but one could hope...
  • Sandi
  • Topic Author
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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14 years 2 weeks ago #18568 by Sandi
Replied by Sandi on topic Re: Rituxan and serum sickness
Usually the pre-meds will prevent during-infusion reactions, but not the delayed ones. They used to be protocol, not sure if they still are.
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