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Prednisone and Levaquin drug interaction FYI

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14 years 7 months ago #12753 by kristilynn
Okay this is more of a warning than anything. I'm taking Prednisone for 5 days as well as Levaquin, an antibiotic. My doc warned me that I should not exercise while taking Levaquin, it can cause tendon ruptures. Neither he or my pharmacist told me that the major drug interaction between these two meds is that the Prednisone ups the risk of tendon ruptures, I looked that up after seeing the Levaquin warning label.
I'm posting because I realize Prednisone is a long-term platelet treatment (I'll never forget that one ) and if you are prescribed Levaquin in the meantime your regular doc or pharmacist may not put 2 and 2 together especially if you don't get the prescriptions filled at the same time.
On the upside I now have a bonafide excuse for avoiding my New Year's exercise resolution :whistle:
  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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14 years 7 months ago #12763 by Sandi
I just had this happen a few weeks ago. I was given Levaquin and am taking 20 mg's of Prednisone. I got achilles tendonitis in both feet (wasn't exercising). I don't think it's going to progress to rupture...it seems to be going away. I was already aware of the warning so when it happened, I knew what was going on. I spoke to my doctor and was told they often prescribe the two together because the reaction is rare. It can happen with those antibiotics even without being on Prednisone. I am at a point where the antibiotics that I can use are so few, I had little choice. Now I have to nix that whole family of antibiotics.