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ITP and Celebrex

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4 years 2 months ago #71660 by Sinfoniarc
ITP and Celebrex was created by Sinfoniarc
Has anybody had any issues using Celebrex while on ITP? I recently had to have a labrum repaired and my orthopedist wanted me to try Celebrex as opposed to using NASIDs - gotta get off of the opioids at some point. Thanks.
  • mrsb04
  • Offline
  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
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4 years 2 months ago #71664 by mrsb04
Replied by mrsb04 on topic ITP and Celebrex
Celebrex is a NSAID
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4 years 2 months ago #71665 by Sinfoniarc
Replied by Sinfoniarc on topic ITP and Celebrex
Yes I know. You're right. I'm referring to other OTC NSAIDs such as Ibuprofen or Aspirin.
  • mrsb04
  • Offline
  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
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4 years 2 months ago #71666 by mrsb04
Replied by mrsb04 on topic ITP and Celebrex
Suggest you discuss it with your haematologist
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4 years 2 months ago #71667 by MelA
Replied by MelA on topic ITP and Celebrex
I'm with mrsb - talk to your hematologist about this.
I had to take baby aspirin for a few weeks after each total knee replacement and he was ok with that as of course we didn't want a blood clot. It actually increased my count for a while.
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD
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3 years 5 months ago #72295 by Rob16
Replied by Rob16 on topic ITP and Celebrex
Celebrex (celecoxib) is an NSAID, but it is a COX-2 inhibitor, not a COX-1 inhibitor. COX-1 is an important part of platelet function, and most NSAIDs have COX-1 inhibiting effects, which is why they should be avoided, especially at counts below 50K.
Celebrex has been shown NOT to interfere with platelet aggregation even at a dosage of 1200 mg/day, while the normal arthritis dosage is much lower, at 200 mg/day.
www.medscape.com/viewarticle/411528
"Study Confirms Celebrex Does Not Interfere With Platelet Function" February 17, 2000
The following user(s) said Thank You: mrsb04
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3 years 5 months ago #72303 by MelA
Replied by MelA on topic ITP and Celebrex
I still won't take Celebrex
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD
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The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.


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