Frequency at night

Does anyone else wake up about 4 times at night to completely full bladder despite not really drinking much?
This is my second time on prednisone after a three year remission but i do not recall waking yp quite so much last time. I also have awful hot flushes and sweat incessantly for hours after i take my dose (about an hour after).
I take 60 mg now (100 the first week) at 7 pm.
Thanks in advance.

aniamaja I don't recall getting up overnight like that - I also took 60mg. I do remember sweating a lot but chalked that up to where we were living at the time (humid Tokyo and Hong Kong).

What time of day are you taking the 60mg?

Prednisone can raise your blood sugar, which can cause more frequent urination.
Prednisone should be taken in the morning, which might help with sleeping at night.
There is such a thing as steroid induced diabetes, so you should let your doctor know.

Prednisone can cause water retention, so yes, frequent urination can be a side effect. It can also raise blood sugar as Rob says, which can also cause it.

I take it at 7 pm because my "doctor" (nurse practitioner - there were no specialist appointments available at my clinic) didn't think it was urgent to call in my prescription earlier in the day when i presented with 15k (a day old result she didn't see fit to confirm).
She evidently didn't think i needed follow up or any information about my treatment plan, side effects or other considerations either, so when after a week on 100mg i took the initiative to show up for a follow up she was "surprised" i was back within normal level. A simple review of my history from 3 years before would have shown her same response to prednizone, albeit monitored every 2/3 days in the initial two week period.
She then proposed to ween me off within a week (80, 80, 60, 60, 40, 20, 10) without consulting a doctor. When i expressed my surprise (last time it took weeks to go down to zero) she offered to consult a doctor and 48 hours and some 10 follow up calls from me later she finally managed to provide the new dose - 60 mg for a week. Despite filling in the symptoms charts, including the frequency and sleep trouble, she did not ask about any of it. In fact when asked about migraine medication she said Excedrin was fine...
Needless to say i am seeing a different doctor at a different clinic tomorrow but just want to know what questions i should be asking - sugar, if it's safe to start the medication much earlier in the day, anything else?

As always, thank you all so much for pitching in!

The body makes its own "prednisone" and does that in the morning - I was told that I should take in the morning, with food. I can imagine you are having a heck of a time if you are taking it at 7pm!

I find this discussion interesting because when I 'had' to use prednisolone I was advised to take it at night because it takes a while to kick in & one is supposed to be able to sleep better before waking up a raving lunatic! :silly: During the day it supposedly lessens so you're not on a 'high' in the evening. Dreadful stuff which ever way one uses it. . .
mj

The previous time i did take it earlier in the day and raving lunatic is not far off... I could have gotten an honorary Italian citizenship for "talking with my hands" lol
I am actually not very hyper this time around, it's just a sensation of suddenly being very hot that in turn causes sweating combined with not being sleepy till 1-2 a.m. (i am naturally a night owl too), but in a non-anxious way. I can deal with all that. It's the getting up 3-4 times that makes me tired i think.

Will see what the new doc says and will report back in case this thread might help someone else. This forum has been a godsend.

High doses of Prednisolone nearly sent me over the edge. I'm now down to 3mg a day taken in the morning and still struggle to sleep. My GP told me once I'm completely of it, it could be months before I was fully over it and back to normal sleep.

An update - i finally got my sugar results back (5 days old) and they are in norm.
Since then though i would say my symptoms have gotten worse, i still get up frequently at night with a full bladder but now also have extremely dry mouth at all times despite drinking gallons of water. I now also sweat throughout the day not just in the evenings and have some dizziness and severe mood swings. The sweats are of the cold and clammy variety, with my arms feeling pretty cold.

They say they will repeat sugar levels on Monday, but in case it really is normal, what else should i be asking to be tested for?

Thanks all in advance!!

Glucose tolerance test might be a good idea

Those seem like typical steroid side effects, so it's hard to say if you should be tested for anything. Your dose is pretty high and was even higher at the beginning. Honestly, I wouldn't know where to tell you to start.

Another update in case this helps anyone else.
The good news - my sugar continues to be low. The bad news, my symptoms calmed down towards the end of last week, but were back again with a vengeance (esp. the frequency) this week. Calming down again as the week progresses.
So my only conclusion is, that my body reacts each time my dose is changed. I was on 50 last week and now on 45 and my doctor wants me to go down 5mg each week, despite going down 10 the previous week, from 60 to 50. Likely because my platelets went up to 489k when i was on 60 and down to 289 when lowered to 50. I guess he is trying to see if it merely dropped to a more normal level or if they are dropping period.
I did not have such a high increase the previous time around or experience change in symptoms with dose changes.
The thought of being on prednisone another 9 weeks is not a happy one but reading other people;s stories i should probably count my blessings.

Slow is better. I know, it stinks!