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immunoglobulins and ITP

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16 years 3 months ago #272 by jk4901
immunoglobulins and ITP was created by jk4901
Immunoglobulins is one method of increasing platelet counts.
What I don't understand about that is that I thought a cause
for ITP is that the body is destroying some of the platelets
as if they were foreign bodies.

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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16 years 3 months ago #276 by Sandi
Replied by Sandi on topic Re: immunoglobulins and ITP
Yes, and IVIG temporarily coats the platelets so the antibodies don't attack them. That's the simplest explanation.

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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16 years 3 months ago #347 by Sandi
Replied by Sandi on topic Re: immunoglobulins and ITP
Update:

I stand corrected. According to newer research, IVIg stops destruction by interacting with the receptors on the macrophages (white cells) that destroy platelets. That means that it affects the antiplatelet antibodies, not the platelets themselves.

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