Meredith, I am taking both Danazol and Promacta.
As you probably know Danazol reduces platelet destruction and Promacta increases platelet production. But when one combines the two, there is a multiplying affect. That is, instead of being an additive affect on counts, it is more synergistic. It works a bit better than either alone.
Let me give a hypothetical numeric example. If a certain dose of Danazol alone raised counts by 40 (from baseline), and, a certain dose of Promacta raised counts by 40 (from baseline), taking both will not raise counts by 80. It will be more like 80 + 20% = 96.
For me. I am taking 100 mg of Danazol and half of a 12.5 mg tablet of Promacta per day. This combination gives a typical count just above 50. Thinking about it with the above example in mind. A full 12.5 mg tablet alone gives me about the same count. But 200 mg of Danazol gave me a 37 count. So an additive effect would have been about 10 (baseline) + 20 (promacta increase) + 14 (danazol increase) = 44. But the count is actually more like: 44 + 20% = 53.
Does that help? LOL, perhaps I'm completely off base and you were actually asking about symptoms?
