My daughter (who is 19) was diagnosed with ITP a few months ago and was taking 100 mg. of Prednisone a day. Prednisone worked, platelets rose, but she's now been tapered completely off and platelets seem to be falling quickly. If the purpose of the Prednisone was to weaken the immune system and therefore, raise platelets, how does that affect the body in terms of it's ability to resist other illnesses? She is pretty sick today (there's respiratory crud going around), coughing, with really deep sounding congestion, and she has a fever. It's Saturday, and we won't be able to reach the doc until Monday. How urgent is it to seek medical care? The only option now is urgent care or the E.R. Does the weakened immune system from Prednisone mean that she won't be able to fight this off? I don't want to overreact, but I also don't want to leave it untreated if that means it becomes harder to treat later, or if the infection will somehow become life-threatening in some way.