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ITP and Cipro

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9 years 1 month ago #55727 by may61967
ITP and Cipro was created by may61967
I am a 73 year old male who recently (five weeks ago) discovered a very low (12,000) platelet level. To date I have been treated with Prednisone and Rituxan. My counts have been variable but have never gotten above 49,000. In reviewing my recent medical history and blood tests this all seems to have started when I had a major UTI which required one day in the hospital. This occured three months ago. I was treated with Cipro which seems to have knocked out the UTI. though I did have a second bout three weeks later which was also treated with Cipro. All in all I had three rounds of the Cipro.

Is there any evidence that a UTI and Cipro can be the cause of ITP? If so is there any best treatment options since nothing seems to be working right now?
  • mrsb04
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  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
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9 years 1 month ago #55728 by mrsb04
Replied by mrsb04 on topic ITP and Cipro
Both medications & infections can cause ITP

medicineworld.org/physicians/hematology/thrombocytopenia.html
  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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9 years 1 month ago #55732 by Sandi
Replied by Sandi on topic ITP and Cipro
Any drug has the potential to trigger ITP. Infections can also.

How long ago did you have Rituxan? What are your counts now?
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9 years 1 month ago #55752 by may61967
Replied by may61967 on topic ITP and Cipro
I started a four week Rituxan series on Sept 9 so I have had 3 infusions so far. My count when I started was 36K, the next week it went up to 49k, but last week it was down to 25K.

At the same time I was tapering off of Prednisone. I was on 20mg a day the first week and none the second week. With the latest results I have been put back on 40mg a day.

Larry
  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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9 years 1 month ago #55756 by Sandi
Replied by Sandi on topic ITP and Cipro
Rituxan can take 4 to 12 weeks to kick in if a person is responsive. My counts went from 3k on the day of the third infusion to 150k the day of the fourth infusion. It can take longer for most people.
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The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.


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