Your adrenals need time to cope with dose reductions. Here is an abridged version of the standard UK Guidelines. Gradual withdrawal for people who have:
Received more than 3 weeks of corticosteroid treatment.
Received more than 40 mg prednisolone daily or equivalent for more than 1 week.
During withdrawal, the dose of oral corticosteroids may be reduced rapidly down to physiological doses (about 7.5 mg of prednisolone or equivalent) and reduced more slowly thereafter. If the problem has resolved and treatment has been given for only a few weeks.
Reduce by 2.5 mg every 3–4 days, down to 7.5 mg per day, then reduce more slowly, for example by 2.5 mg every week, fortnight, or month. If there is uncertainty about disease resolution and/or therapy has been given for many weeks.
Reduce by 2.5 mg every fortnight down to 7.5 mg per day, then reduce by 1 mg every month.
These are the latest guidelines from uptodate .com
-5 to 10 mg/day every one to two weeks from an initial dose above 40 mg of prednisone or equivalent per day.
-5 mg/day every one to two weeks at prednisone doses between 40 and 20 mg/day.
-2.5 mg/day every two to three weeks at prednisone doses between 20 and 10 mg/day.
-1 mg/day every two to four weeks at prednisone doses between 10 and 5 mg/day. (personally I would say 7.5mg)
-0.5 mg/day every two to four weeks at prednisone doses from 5 mg/day (personally again I would say 7.5mg) down. This can be achieved by alternating daily doses, eg, 5 mg on day one and 4 mg on day two.
It can take ages to get off them. I can't cope with more than 0.5mg/day /month otherwise I have horrific withdrawal symptoms.
The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.
Platelet Disorder Support Association 8751 Brecksville Road, Suite 150, Cleveland, Ohio 44141 Phone: 1-87-PLATELET | 877-528-3538 (toll free) | or 440-746-9003 E-mail: email@example.com