This phase two open-label study is designed to assess the safety and efficacy of using Zanubrutibin, a selective next-generation covalent BTK inhibitor, to treat immune thrombocytopenia. Zanubrutinib was developed by a company in China to be a stronger BTK inhibitor with less side effects. Eligible participants include adult patients with confirmed persistent or chronic ITP who have a platelet count less than 30,000µL and demonstrate corticosteroid resistance and failure to respond to at least one approved second-line therapy. The study is looking to enroll 30 participants.
China
https://www.clinicaltrials.gov/ct2/show/NCT05214391?recrs=a&cond=Immune+Thrombocytopenia&draw=2&rank=25
Status: unknown