Season 2 Episode 28  |  December 15, 2025

Understanding the Difference Between Inherited and Immune Thrombocytopenia

This episode dives into one of the most common—and most confusing—questions people with ITP ask: Why do I have it, and could it be inherited? Dr. Michele Lambert, a leading pediatric hematologist and expert in platelet disorders, breaks down the difference between inherited thrombocytopenia and immune-mediated ITP in clear, relatable terms. She explains how genetics, immune system “confusion,” family history, and targeted testing all play a role in getting the right diagnosis—and why that matters for choosing the most effective treatment. Whether you're newly diagnosed or have lived with ITP for years, this conversation offers eye-opening insights, practical takeaways, and real hope for more personalized care in the future.

Lifestyle Tip:
Barbara explains how genetic testing might offer clarity when your family history is missing or uncertain.

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PDSA Resources:

Bruised but not Broken: Living with ITP Season 1 Episode 4
- Family History and ITP: Uncovering Genetic Clues

Bruised but not Broken: Living with ITP Season 1 Episode 7
-Demystifying Genetic Testing for ITP Patients

Bruised but not Broken: Living with ITP Season 2 Episode 25
- From Patient to Pediatric Immunologist: Dr. Kristin Hunt's Guide for Patients and Parents

When It's Not ITP

Inherited Thrombocytopenias: Other Platelet Disorders

ITP and Genetics


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