Search Results (Searched for: tamiflu)

  • MelA
16 Aug 2023 14:14 - 16 Aug 2023 14:17
Replied by MelA on topic Tamiflu
Oseltamivir was well tolerated with a good overall response rate and was useful for treating chronic ITP. We observed an initial increase in the number of platelets; however, this response was not maintained
Apr 26, 2022
National Institutes of Health (.gov) pubmed.ncbi.nlm.nih.gov  › ...
  • Lhjohns48
15 Aug 2023 10:44
Tamiflu was created by Lhjohns48
Has anyone had a positive increase in platelets from having the Tamiflu series of drugs when you’ve gotten the flu type a?   My platelets were down to 70,000 and I got the flu and took the Tamiflu medication for seven days or whatever it was and my platelets jumped up to 400,000 and they’re still just gradually coming down; I’m at 200 now about three months later. Interesting …..makes me wonder what’s in the Tamiflu and if any research has been done.
  • MelA
29 Jun 2022 00:18
Replied by MelA on topic Tamiflu (Oseltemivir)
Sorry you haven't received any replies PennyH - probably no one has tried Tamiflu as a treatment.
Good luck to you!
  • PennyH
17 Jun 2022 16:26 - 17 Jun 2022 16:27
Tamiflu (Oseltemivir) was created by PennyH
Hi,
has anyone tried the above.  My haematologist has tried all available meds in New Zealand and my count is still under 10.  In desperation she is trialling me in Tamiflu.
interested to know if anyone has tried it.
Thanks
Penny
  • Hal9000
10 Apr 2020 16:20 - 10 Apr 2020 16:22
Replied by Hal9000 on topic New articles posted here - update 6-28-17

rwrourk@gmail.com wrote: 83 yr old post splenectomy as a child - count usually around 98,000, but when I had the Type A Flu in January 2020 (now wonder if it was COVID) and count went down to 30,000. After 2 days in hospital pumped full of TamiFlu, Azityromycin, IV fluids and 1 IV dose of Prednisone, at 10 day follow-up with my Internist, platelet count 450,000! It has never in my lifetime been that high. Weird! Anyone else had a similar experience?

If you do a search on PDSA website of the word 'TamiFlu' you'll find ITP'ers who have reported count rises with it.
pdsa.org/discussion-group/search.html?query=TamiFlu&searchdate=all&order=inc&childforums=1&limit=30&start=0
Specifically users: 'Tara0815' and 'semd'.

Thread on the subject of TamiFlu:
pdsa.org/discussion-group/7-treatment-general/28670-tamiflu-and-increased-platelet-count-in-husband.html#48148

Best I can gather,
1) those that respond to TamiFlu are either row 2 or row 2/1 in my treatments table. Other ITP'ers don't get a count rise with the drug.
bottools.com/Hal/ItpTypes.html

2) Flu Type A(H3) seems to cause the most trouble. Newly triggered ITP or relapse either one.
pdsa.org/discussion-group/7-treatment-general/30169-no-response-to-ivig-ack.html#65712

If you go to CDC data on the Flu, and click on 'group by virus', it looks like A(H3), A(H1N1), and B(Victoria) are the Flu strains active right now.
gis.cdc.gov/grasp/fluview/flu_by_age_virus.html

If you want to get a better understanding of what is theorized to be going on, on that first link above, look for 'desialylation' (or desilylated) and what that is and does to platelets. It's all about the liver.
  • rwrourk@gmail.com
30 Mar 2020 09:36
Replied by rwrourk@gmail.com on topic New articles posted here - update 6-28-17
83 yr old post splenectomy as a child - count usually around 98,000, but when I had the Type A Flu in January 2020 (now wonder if it was COVID) and count went down to 30,000. After 2 days in hospital pumped full of TamiFlu, Azityromycin, IV fluids and 1 IV dose of Prednisone, at 10 day follow-up with my Internist, platelet count 450,000! It has never in my lifetime been that high. Weird! Anyone else had a similar experience?
  • MelA
19 Feb 2020 10:24 - 19 Feb 2020 10:25
Replied by MelA on topic Looking for advice
Your rheumatologist said you had the flu? You don't know for sure without a test.
A dear friend recently was tested and she was Flu A - put on tamiflu.
Or did your rheumatologist say you had osteoarthritis?

Hope you are feeling better now!
  • Turbo01
21 May 2019 21:03
Replied by Turbo01 on topic My Child has ITP only 8 months old
Hi Nanuka,

How wonderful I’m so happy to hear that your little ones numbers went so high.

March 22 my daughter got her 3rd ivig her numbers dropped to 8,000 due to getting the flu in school. Thankfully tamiflu got rid of the flu fast and the ivig brought her numbers up high and seems to be doing pretty well on her own. Her last CBC was May 17 with a not normal but good number of 123,000.

Within the 2 months we had very few symptoms of petechia just 1-3 dots here and there. The good news is that we saw another hemo in NYU in Manhattan NY. She was very helpful although couldn’t tell me if my daughter will outgrow she gave me relief in telling me that it isn’t anything else wrong other than itp.

Please keep me posted I. Your child’s progress as I will too. Be strong!
  • Sandi
21 Mar 2019 16:09
Replied by Sandi on topic Tamiflu ??
The claims are that Tamiflu will only lessen symptoms by 12 hours or less. It doesn't cure the flu or treat it.
The best prevention is Vitamin D and Vitamin C. If she would get the flu, you could probably use NSAIDS if her counts are over 50k at the time. I'd check with her doctors.

www.ncbi.nlm.nih.gov/m/pubmed/22156085/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4375804/?fbclid=IwAR3L3AInpwratszGs5Lp-yGksVMNB8GWhNdCHlM1TbbBtzA8cg145tzCHrk
  • Turbo01
23 Feb 2019 12:59
Tamiflu ?? was created by Turbo01
Hello my daughter is 5 with itp levels drop when she is sick only. She has not had the flu shot as doctors said she shouldn’t since she had ivig. Hopefully she won’t need it but suppose she does get the flu is tamiflu safe for children with ITP??

Last year we had a terrible battle with the flu and we had to alternate Motrin and Tylenol. But since she was diagnosed with itp we know Motrin is a No No. how would we treat?

Thank you all in advance you have all been so good and supportive to us.
  • Sandi
14 Nov 2018 17:54
Replied by Sandi on topic SInce it's flu season....
"But as Jeanne Lenzer, an independent reporter and associate editor at the medical journal BMJ points out in a recent article, there’s a big problem with Frieden’s advice: The Food and Drug Administration (FDA) has determined that the clinical trial data submitted to it for review does not support the claim that Tamiflu “saves lives” or even reduces hospitalizations, including for the elderly and others most at risk."

www.minnpost.com/second-opinion/2015/02/cdcs-advice-take-tamiflu-compromised-financial-conflicts-interest/?fbclid=IwAR3ha_iuoMxLrwFa53y6w_9gQpZ-K2-W_0IQr5gbRLzqyj71vEH8359mZpI
  • Sandi
14 Nov 2018 17:48
Replied by Sandi on topic SInce it's flu season....
And yet, they are still prescribing it.

"Oseltamivir (Tamiflu), a neuraminidase inhibitor, was approved for seasonal flu by US Food and Drug Administration in 1999. A number of randomized controlled trials, systematic reviews, and meta-analysis emphasized a favorable efficacy and safety profile. Majority of them were funded by Roche, which also first marketed and promoted this drug. In 2005 and 2009, the looming fear of pandemic flu led to recommendation by prominent regulatory bodies such as World Health Organization (WHO), Centers for Disease Control and Prevention, European Medicines Agency and others for its use in treatment and prophylaxis of influenza, and it's stockpiling as a measure to tide over the crisis. Serious Adverse Events, especially neuropsychiatric events associated with Tamiflu started getting reported leading to a cascade of questions on clinical utility of this drug. A recent Cochrane review and related articles have questioned the risk-benefit ratio of the drug, besides raising doubts about the regulatory decision of approving it. The recommendations for stockpiling the said drug as given by various international organizations viz WHO have also been put to scrutiny. Although many reviewers have labeled the Tamiflu saga as a “costly mistake,” the episode leaves us with some important lessons. This article takes a comprehensive relook on the subject, and we proceed to suggest some ways and means to avoid a similar situation in the future."

www.ncbi.nlm.nih.gov/pmc/articles/PMC4375804/?fbclid=IwAR3L3AInpwratszGs5Lp-yGksVMNB8GWhNdCHlM1TbbBtzA8cg145tzCHrk
  • Sandi
30 Sep 2018 00:26
SInce it's flu season.... was created by Sandi
I thought you guys might want to be aware of this:

OBJECTIVE: To examine the epidemiological association between sudden deterioration leading to death and Tamiflu use.
DESIGN: Proportional mortality study.
SETTING: Japan.
PARTICIPANTS: 162 deaths without deterioration before the first consultation among all 198 deaths of mostly confirmed 2009A/H1N1 influenza. POPULATION AT RISK: Age-specific population of influenza patients prescribed Tamiflu and Relenza.
MAIN OUTCOME MEASURE: Age-stratified pooled odds ratio (OR) for early (within 12 hours) deterioration and overall death of Tamiflu prescribed to Relenza prescribed patients.

RESULTS: Of 119 deaths after Tamiflu was prescribed, 38 deteriorated within 12 hours (28 within 6 hours), while of 15 deaths after Relenza, none deteriorated within 12 hours. Pooled OR for early deterioration and overall death were 5.88 (95% CI: 1.30 to 26.6, p = 0.014) and 1.91 (p = 0.031) respectively. Baseline characteristics including risk factors did not contribute to early deterioration after Tamiflu use.

CONCLUSIONS: These data suggest Tamiflu use could induce sudden deterioration leading to death especially within 12 hours of prescription. These findings are consistent with sudden deaths observed in a series of animal toxicity studies, several reported case series and the results of prospective cohort studies. From "the precautionary principle" the potential harm of Tamiflu should be taken into account and further detailed studies should be conducted.

www.ncbi.nlm.nih.gov/m/pubmed/22156085/

Maybe not worth it for only a 12 hour reduction in flu symptoms?
  • Hal9000
25 Jul 2018 11:15 - 25 Jul 2018 13:41
Some would probably say, 'whatever it takes to get off Pred !'
Seriously, those numbers sound good. Not too low, not too high, but just right. Marginally increasing too, another good sign.

Yea, I couldn't find much on Etanercept and ITP either. That alone raises a yellow flag.

On the Indium scan. Do they allow you to be on IVIG and Fostamatinib for the test? I can see how there is no drug which blocks liver destruction of platelets (except Tamiflu) and that is how the test achieves its accuracy. But it seems to me that a lot of drugs block splenic destruction and that is what leads to inconclusive results. Taking drugs during the test.
  • libelder
13 Apr 2018 17:42
Replied by libelder on topic Nplate, fibrosis, Promacta
You're right Hal, doc felt the fibrosis was not serious and wasn't prepared to say Nplate related since I'm over 60 and it can happen with age. What I've seen indicates Nplate and Rituxin play OK together, I'm pretty sceptical of the tamiflu so don't expect to try it- it just has too much of a random "let's try the kitchen sink" feel to it for my comfort, and cyclosporin failed years ago so I'm even less inclined to try CellCept... But sh*t, you know? I damn near died Monday night, I was alone and where there was no 911 service and I went from OK to NOT so quickly, it rattled me. If I can just hold on til the fostamatinib comes out I think that might be the one for me, but I wish we knew when that'll happen. Thanks for your input.
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