Association of platelet parameters with bleeding severity in children with ITP

Boston Children’s Hospital is conducting an observational cross-sectional study in hopes to replicate larger scale findings from smaller studies that suggest a positive correlation between platelet parameters (such as immature platelet function, absolute immature platelet count, and P-selection and glycoprotein 11b-11a) with bleeding severity in severe immune thrombocytopenia, regardless of platelet counts. This study center hopes to confirm previous findings in a multi-center patient population to investigate the use of these parameters and better predict disease severity and bleeding events.



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