Has anyone here received Evusheld? My daughter has ITP and Nodal Marginal Zone Lymphoma and has not been able to receive any Covid vaccines due to allergies and receiving Rituximab, I was very encouraged to find out about Evusheld as a prophylactic until I saw the warnings about any coagulant issues and possible heart problems. Now I am not sure what to think.
I've got lymphoma and am on rituximab too. We don't have access to this drug yet in the UK but I would have it if I could. They're into treatment with Sotrovimab here rather than prevention, presumably because it's cheaper to wait until we catch covid than to try to prevent it. It seems unfair but nothing we can do.
Although on rituximab I've still received the vaccinations just in case it has some effect. Some studies have shown a T-cell response in patients using rituximab so I thought it worth a try. I am due a fourth vaccination round about now.
I had two Evusheld doses. No side effects. Am 75. Doctor told me cardiac symptoms were rare. But, AstraZeneca did their clinical trials before Omicron. They claim it will kill Omicron because it does in a test tube. There were no clinical trials with humans during Omicron. That is why the FDA revised its EUA and second doses were given. I got no benefit from two Moderna shots - immunosuppressed. I have no idea if there two Evusheld shots will give me any protection. I don't think anyone does. I continue to mask and stay out of restaurants and crowded places.
Thank you for sharing your experience, as it turns out she actually had Covid when I posted this question. I asked that they run an antibody test at her Rituximab treatment in Feb and she had antibodies. With all things considered, she did quite well. She was quite sick but I blamed it on her treatment a few weeks before and the platelet meds that she is on. She is still homebound except for her Dr appts, one more treatment to go and then maybe back to having a life at some point down the road, I'm thinking probably October IF Covid has settled down. Not sure if her Dr is going to suggest Evusheld at this point, he never really seemed all on board due to her double whammy going into it.
I did six rituximab with bendamustine chemo (one every four weeks), and now maintenance ritux for two years. It's often done every eight weeks but I opted for every twelve weeks because I was fed up with them! So I will do eight maintenance doses.
Evusheld has now been approved in the UK but we don't think that the government has actually ordered any so we still can't get it.
To what country are you referring? I got two doses of Evusheld after the FDA (U.S.) decided one was not enough. I got 150MG twice. The clinical trials were conducted with 5000 humans before Omicron (Delta). They then did test tube trials (in vitro) and found it killed Omicron in a test tube. But, it has not been shown to kill Omicron in a human. Very confusing. The FDA then suggested getting another dose. So I have the stuff in me and no idea if it works. I am immunosuppressed. Also, my platelets, stable at 48, dropped to 34 after the two doses. No one is collecting this kind of data. I will not change my behavior. I have no confidence this is any good.
I am 75. Retired also. No IgA and low Lymphocytes. Was initially excited about Evusheld, but then was disappointed as more information leaked out. Government paid $1700 U.S. for each of my two doses. Maybe the U.K. is smarter. Initially, it looked like their claim that it protected against Omicron was tied to the clinical trial in vivo. It turns out the foundation came from in vitro work. Bleach would kill it in vitro. Who will take bleach? You may or may not be missing anything of value. The data is questionable. Sorry you are having another variant there now. Coming here fast. I retired from healthcare also.
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