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Highest N-PLATE dose

  • amberyard
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  • Lowest count 0-1k highest count 1,247,000 11/2/21. 189,000 N-Plate 527 Weekly CBC
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4 years 8 months ago #66939 by amberyard
Highest N-PLATE dose was created by amberyard
There are only 3 drugs I haven't tried.
1. A male hormone
2. A chemotherapy pill
3. Cyclosporine, imuran
My current N-Plate dose is 531mcg, B12 monthly and vitamin D3 once a week. Platelets today 134 and last week 204. I normally crash around holidaysI know N-Plate will at some point stop working.
I'll add blood work also

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  • Hal9000
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  • Give me all your platelets and nobody gets hurt
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4 years 8 months ago - 4 years 8 months ago #66956 by Hal9000
Replied by Hal9000 on topic Highest N-PLATE dose
From 700 mcg down to 531 mcg? Sounds like things are going well.
My guess would be that Cyclosporine has the highest chance/probability of helping on that list. But, it is toxic to kidneys. 'Dr Bean' takes low doses of it with Promacta. I think he doesn't respond to Promacta without simultaneous Cyclosporine.
If you lose response to Nplate maybe you can ask your doc about higher doses of Promacta? Higher than the normal 75 mg. Some here on PDSA have gone on up to 150 mg dosage and it is working.
The following user(s) said Thank You: amberyard

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4 years 8 months ago #67105 by JJ
Replied by JJ on topic Highest N-PLATE dose
Sounds like you are doing just fine. Nplate probably won't stop working. It doesn't for most. You could probably lower the dose and still be above 50.

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  • mrsb04
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  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
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4 years 8 months ago #67112 by mrsb04
Replied by mrsb04 on topic Highest N-PLATE dose
My count was never stable on Riomiplostim it swung about all over the place.

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