My hema is leaving medicine and pursuing another career. My new one has said I may have to go on Fostamatinib an oral syk inhibitor ( apparently this has just been approved) I have been trying to find out info on it but can only find articles that are way "above my head" , so my question is: are there any articles out there put in general layman's terms or can anyone give me simplified info on the drug.
I am currently on Revolade 100 mcgs (?) with a gamma transfusion aprox once a month. It has been like this for a couple of years, I like to think if it "ain't broke don't fix it"
Thanks and high platelets everyone
That is unfortunate about your hematologist leaving. I don't know much about Fostamatinib. The little I've heard or read didn't make it sound promising, so didn't do any research into it. However, it may work for you. It does for some. To me, seems like the better idea would be to find a different hematologist who will let you stay with the treatment that has worked for you for a number of years. Is that possible?
Here is the simple explanation from the manufacturer of fostamatinib/Tavalisse.
My hematologist also suggested that I might want to switch from Nplate to Tavlisse. No thank you. I am happy that I've found a drug that works without noticeable side effects-Nplate, so no reason to experiment with a new drug. Plus Tavalisse costs $10,500 per month for the lowest dose and I don't qualify for the co-pay program. That said, my hemo said he has a few patients on Tavalisse and it is working for them. Its good to have options. I have heard that Tavalisse is 45% effective from trials and Eltrombopag/Nplate are about 80% effective- don't have those references, just what I've heard.
Diagnosis of ITP in 2014. Ex renal specialist nurse. I retired in Nov 2019 after 46 years on the front line. I firmly believe in empowering patients to be involved as much as possible in their care; always question medics about the evidence base they use.
Thank you received: 421
Don't be forced into any treatment you are not sure of.
Fostamatinib isn't all it is cracked up to be in my opinion. 18% success rate in the trials. I was one of the 82% it did not work for. Still not licensed for ITP in the UK.
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