Article re: pros and cons of treatments

Article re: pros and cons of treatments 8 years 6 months ago #32487

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	I came across this article today and have no idea how I missed it in my Bloodjournal updates. It's one of the most thorough treatment articles I've ever read, listing pros and cons of three common treatments. bloodjournal.hematologylibrary.org/content/120/5/960.full?sid=9e00c230-10f8-405a-964d-299484e271a0 The following user(s) said Thank You: Nomad, Dori, Fervenz, johnmerrick
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Article re: pros and cons of treatments 8 years 6 months ago #32493

CindyAnn Offline Diagnosed Jan 10, 2008. Rituxan treatment in May 2009. Treated with Prednisone off and on until 08/23/17 - 12.5mg Promacta as of 10/22/17 Posts: 227 Thank you received: 39	This article sure makes a good argument for delaying a splenectomy. It also points out the many choices we as "ITPers" have to make. Very good read!!! Cindy Ann
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Article re: pros and cons of treatments 8 years 6 months ago #32505

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	I think the article presents both sides well, but does give examples of when it is best to consider it and best not to.
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Article re: pros and cons of treatments 8 years 6 months ago #32514

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	Here's another good article that I just found: bloodjournal.hematologylibrary.org/content/118/16/4297.full?sid=6289f8c7-0a84-4a8d-93cb-7f281787cd36
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Article re: pros and cons of treatments 8 years 6 months ago #32523

Vdeutsch85 Offline Posts: 723 Thank you received: 121	Great article, one article says to wait 1-2 years before considering splenectomy and the other says 3
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Article re: pros and cons of treatments 8 years 6 months ago #32528

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	I looked to see the time difference between the two articles...only 8 months. Different authors too. Oh well, safe to say they advise to wait one to three years!
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Article re: pros and cons of treatments 8 years 6 months ago #32548

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	www.ncbi.nlm.nih.gov/pubmed/23637127
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Article re: pros and cons of treatments 8 years 6 months ago #32554

Vdeutsch85 Offline Posts: 723 Thank you received: 121	I think I will re-assess my situation in December....that will be the one year point for me. However, the more I read, the more against splenectomies I become.
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Article re: pros and cons of treatments 8 years 5 months ago #33247

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	Here is a new article re: Rituxan and Dexamethasone. This has been published before, but the more this combination is studied, the more credible it becomes. onlinelibrary.wiley.com/doi/10.1111/ejh.12102/abstract The following user(s) said Thank You: Dori
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Article re: pros and cons of treatments 8 years 5 months ago #33255

Vdeutsch85 Offline Posts: 723 Thank you received: 121	Thank you for sharing!
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Article re: pros and cons of treatments 6 years 7 months ago #47722

goaliegirl51 Offline Posts: 4 Thank you received: 0	I had a laproscopic splenectomy after having all possible treatments attempted. It worked great for about a month. Then my platelets plummeted again. I now have an n-plate injection every week.
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Article re: pros and cons of treatments 6 years 7 months ago #47723

EmilyK Offline Diagnosed jan 2015 at age 50 with 13,000 platelets. Posts: 454 Thank you received: 67	How is the NPlate working for you?
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Article re: pros and cons of treatments 6 years 7 months ago #47725

goaliegirl51
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Well it does the job. Generally you're supposed to keep the platelets between 50,000 and 150,000, but I'm so messed up I don't actually follow all of the FDA recommendations. In general though, I'd say it's painless. You have to stay on top of it. If you miss a dose, your count will plummet. My doctor advised me to use Nplate instead of the promacta pill because apparently the pill is a bigger pain and diet restrictions. Supposedly most people dislike the pill way more than Nplate.

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Article re: pros and cons of treatments 6 years 7 months ago #48147

Sandi Offline Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18 Posts: 12435 Karma: 11 Thank you received: 2366	Goalie: It's in your best interest to follow the Guidelines for N-Plate. Not doing so can be dangerous. Counts should actually be maintained around 50k and your doctor should be dosing you in that manner.
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Article re: pros and cons of treatments 6 years 7 months ago #48150

mrsb04 Offline Diagnosis of ITP in 2014. Retired (Nov 2019) renal specialist nurse, 46 years on the NHS front line. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use Posts: 1897 Karma: 7 Thank you received: 545	Interesting reads thank you Sandi
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