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ITP and Celebrex 1 year 2 months ago #71660

  • Sinfoniarc
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Has anybody had any issues using Celebrex while on ITP? I recently had to have a labrum repaired and my orthopedist wanted me to try Celebrex as opposed to using NASIDs - gotta get off of the opioids at some point. Thanks.

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ITP and Celebrex 1 year 2 months ago #71664

  • mrsb04
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  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
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Celebrex is a NSAID

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ITP and Celebrex 1 year 2 months ago #71665

  • Sinfoniarc
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Yes I know. You're right. I'm referring to other OTC NSAIDs such as Ibuprofen or Aspirin.

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ITP and Celebrex 1 year 2 months ago #71666

  • mrsb04
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  • ITP since 2014. Retired nurse. My belief is empower patients to be involved as much as possible in their care. Read, read, read & ALWAYS question medics about the evidence base they use.
  • Posts: 2023
  • Karma: 7
  • Thank you received: 575
Suggest you discuss it with your haematologist

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ITP and Celebrex 1 year 2 months ago #71667

  • MelA
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I'm with mrsb - talk to your hematologist about this.
I had to take baby aspirin for a few weeks after each total knee replacement and he was ok with that as of course we didn't want a blood clot. It actually increased my count for a while.
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD

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ITP and Celebrex 5 months 2 weeks ago #72295

  • Rob16
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Celebrex (celecoxib) is an NSAID, but it is a COX-2 inhibitor, not a COX-1 inhibitor. COX-1 is an important part of platelet function, and most NSAIDs have COX-1 inhibiting effects, which is why they should be avoided, especially at counts below 50K.
Celebrex has been shown NOT to interfere with platelet aggregation even at a dosage of 1200 mg/day, while the normal arthritis dosage is much lower, at 200 mg/day.
www.medscape.com/viewarticle/411528
"Study Confirms Celebrex Does Not Interfere With Platelet Function" February 17, 2000
The following user(s) said Thank You: mrsb04

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ITP and Celebrex 5 months 2 weeks ago #72303

  • MelA
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I still won't take Celebrex
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD

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