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This is nuts - baby aspirin raises my count 2 years 9 months ago #68485

  • MelA
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-February 2019 I had total knee replacement on right knee - to keep from getting blood clot/s I was put on 2 baby aspirin a day for 30 days.
My count went up to 220,000 2 weeks into the 30 days.
-November 2019 I had total knee replacement on my left knee - to keep from getting blood clot/s I was put on 2 baby aspirin a day for 30 days.
My count went up to 197,000 2 weeks into the 30 days
-My count is going down, as of yesterday it was 97,000

Just curious if anyone else has had to go on baby aspirin for a while and their count went up?
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD

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This is nuts - baby aspirin raises my count 2 years 9 months ago #68492

  • ecoclayton
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I feel like I have seen on these discussion boards somewhere before about this happening after knee surgery. I feel like people thought the body was more worried about the knee recovery than the platelet destruction. Maybe try the baby aspirin again without any surgery to see what happens?

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This is nuts - baby aspirin raises my count 2 years 9 months ago #68497

  • MelA
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Hi ecoclayton - that was me who posted about my count going up while on the baby aspirin last year, it was my right knee replacement. I think it may have been Hal's guess that the body was more concerned about the surgery & forgot to destroy the antibody covered platelets. I thought it was just a fluke my count increased with the baby aspirin 2x a day when the knee was replaced - but since it happened again 9 months later when the left knee was replaced and I was again put on baby aspirin 2x a day for 30 days now I don't think it was a fluke.

I won't try baby aspirin again unless needed - don't care to tempt fate. My luck I'd crash :)
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD

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This is nuts - baby aspirin raises my count 2 years 9 months ago #68550

  • Hal9000
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Melinda, to be clear. The evidence I was using for my guess is that everyone here that has had a knee replacement has likewise experienced an extended count increase afterwards, as you have.

And evidence of my own experience. When my appendix was removed I myself had an increase to 130 or so a week later. There was no drug of any kind taken during that period. Only IV antibiotics (and platelets) before surgery. Counts had returned to my baseline of 12 a month later.

There was a suggestion that even with a failed splenectomy, counts will increase for a short period afterwards. Perhaps for the same reason: surgery on the body.

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This is nuts - baby aspirin raises my count 2 years 9 months ago #68555

  • MelA
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Hal did you ever guess that it was the antibiotics that increased your platelets? Lots of people here have had an increase of counts with antibiotics [not everyone though].

Of course with a failed splenectomy counts will increase for a short period - the spleen is no longer there to destroy the platelets so they live on, that is until other blood cleaning locations in the body take over destroying the antibody covered platelets and the count goes down again.

Who are the "everyone here" with knee replacements & extended count after. My count was only extended during the time I was taking the baby aspirin 2x a day.
"Instead of wasting your time worrying about symptoms, just get it checked out" -Nieca Goldberg, MD

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This is nuts - baby aspirin raises my count 2 years 8 months ago #68669

  • Hal9000
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Hal did you ever guess that it was the antibiotics that increased your platelets?

Yes, I wondered about that. But, that was before learning how high counts go after knee surgery.

Lots of people here have had an increase of counts with antibiotics [not everyone though].

Yes. There is one antibiotic in particular that seems to raise counts very well / reliably for ITP folks. But I don't recall the name off hand.

Of course with a failed splenectomy counts will increase for a short period - the spleen is no longer there to destroy the platelets so they live on, that is until other blood cleaning locations in the body take over destroying the antibody covered platelets and the count goes down again.

Who are the "everyone here" with knee replacements & extended count after. My count was only extended during the time I was taking the baby aspirin 2x a day.

Here is the list I posted earlier:
pdsa.org/discussion-group/6-general-itp-discussion/30295-odd.html#65980

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