Dean - I'm not arguing with you, just trying to understand. First, is it a fact that low serotonin causes depression? How could one person escape depression from low serotonin and another not? It's a medical condition.
Second, if platelets are low and therefore serotonin is too, again, how could some people not be depressed and others are? Serotonin is a measured chemical so the levels probably dictate how a person reacts to a degree.
Third, I think it's hard to distinguish whether a person is depressed because they have to deal with ITP or the depression is a direct result of the ITP. You can take two people both diagnosed with counts of 5k. One cries and frets and the other shrugs and thinks it's no big deal. I have always thought that attitude dictated more than serotonin.
Now please understand, I was also one who cried and worried and can honestly say that I did get depressed, but I also know it was after the ITP diagnosis and I was depressed because of the diagnosis. Well, maybe not depressed, but scared. I did become depressed after high Prednisone doses and that was considered steroid-induced depression. After I was on Celexa for a while though, I was fine. I also changed my attitude about ITP and went with the flow. No more depression after that.
I'd still like to see some sort of clinical article about low platelets and serotonin.