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N Plate 1 month 4 weeks ago #72515

  • Carducci7292
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  • Posts: 76
  • Thank you received: 9
I am finishing my third year on N Plate. I am extremely lucky in that for the the last two and one half years, my counts have been above 100,000 and 90% of the time above 140,000. During that time I have been receiving 1 mcg/kg. I have had 6 occasions when my counts were above 200,000 for two consecutive weeks and then fell below 200,000 the third week. In accordance with N Plate's parameters I would have reduced 1 mcg which in my case would have meant no injection. My hematologist and I have discussed going to a 1 mcg/kg injection every other week but were hesitant to do so during the pandemic. We are now discussing it again. I was wondering if anyone has experience or knows of someone who has had a similar situation and what happened when they spread out their injections from weekly to something longer? My hematologist said he had two patients whose counts dropped severely and then stabilized and came back up somewhat after doing so.
Thank you

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N Plate 1 month 4 weeks ago #72516

  • JJ
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I did it like that. Did injections further and further apart up to about once every five weeks and then stopped altogether. My counts didn't drop low at that time but stabilised around 80. Counts did drop again a few years later and I did nplate for a few months and when my count went too high, I stopped again.

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N Plate 1 month 4 weeks ago #72517

  • Carducci7292
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Can I ask what your counts were before you started to stretch out the injections? Did you see a drop each time you lengthened the time between injections?
Thank you very n=much for responding.

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N Plate 1 month 4 weeks ago #72521

  • midwest6708
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  • ~ Janet ~ Diagnosed Sept. 2008
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I get Nplate weekly but have been getting less than 1 mcg per kg for years.  I weigh 61kg and my dose is 40 mcgs.  My counts are rarely in the ideal 50 range.  They're generally between 60 and 100, which is okay with me.  When the counts begin moving above 100 with regularity, the dose gets dropped by 5 mcgs. Skipping doses makes them even more erratic and is unacceptable to me.
My point is, success can be had with doses of fractions of 1 mcg per kg.
The following user(s) said Thank You: Carducci7292

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N Plate 1 month 3 weeks ago #72544

  • JJ
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My counts were over 100 for a few months, testing only every four weeks.. 102, 136, 102, 103 etc. So I did every other week for a while.  Then as they stayed over 100 stretched it out further. Eventually my count went over 200 so I stopped altogether. We don't inject if over 200.  I was then off it for over four years and crashed down to 1. Did Nplate again for eight weeks, count 184 and stopped.

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N Plate 1 month 3 weeks ago #72545

  • Carducci7292
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Interesting here they won't inject if you test over 200 for three consecutive weeks or if you go over 400. They won't increase your dose of start injections unless you are under 50. 
Can I ask how long it took after you stop the injections to go over 200 and were you over 200 at any time prior to stopping? Also, do you have any idea why you dropped to 1 i.e. were you ill or something else?
Thank you very much

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