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HLA Matched Platelets

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4 years 3 weeks ago #68989 by cliffsails
HLA Matched Platelets was created by cliffsails
I am a 73 yr old male that was diagnosed with MDS 3 1/2 years ago. After being on chemo (Vidaza) for 3 yrs it stopped working. I went on a Vidaza + Venoclax routine for 4 months but BMB showed a continued decline in my Blast counts and am now on a Cytarabine + Daurismo routine. My platelet counts ( and WBC, RBC, Hg) during this time have continually dropped. They now seem to hover at around 2-4 and have been as low as 0. Platelet(irradiated) infusions don't seem to bring the platelet count up. I am now told to try HLA Matched platelets. I am asymptomatic with only purpura and petiche on my arms and legs. Has anyone had the same experience or experience with HLA Matched platelets? Did it make a differncence?

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4 years 3 weeks ago #68990 by JJ
Replied by JJ on topic HLA Matched Platelets
We here have ITP which means we kill off our own platelets so receiving any platelet transfusion including antigen matched wouldn't help. So I fear that nobody here will have had the experience you are looking for. Good luck.

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